In its inaugural year, MAGISNAT (https://magisnat.com/) set an ambitious goal: to redefine personalized wellness by offering a holistic, science-based approach to prevention and self-care, typically available only in premium wellness clinics. Based in the state-of-the-art Atlanta Tech Park in Peachtree Corners, GA, MAGISNAT has introduced an integrated system that leverages genomic, metabolomic, proteomic, and microbiomic analyses to deeply understand individual biological needs. This enables the development of scientifically guided yet accessible strategies for improved nutrition and lifestyle.
The DNA Wellness Test: Advanced Omics for Health Insights
The DNA Wellness Test stands out as one of MAGISNAT's most sophisticated tools for gaining detailed insights into individual health. By analyzing 121 single nucleotide polymorphism (SNPs), the test focuses on four key areas:
1. Vitamin and Mineral Metabolism
The test evaluates how the body processes essential vitamins like A, B6, B9, B12, C, D, E, and K, crucial for immune support, cell growth, and bone health. This analysis identifies specific supplementation needs to address deficiencies effectively.
2. Metabolism of Carbohydrates, Lipids, and Proteins
It provides precise information about the body's handling of sugars, fats, and proteins, enabling strategies to control weight and optimize dietary responses.
3. Detoxification and Antioxidation
By assessing the body's ability to eliminate toxins and combat oxidative stress, this module highlights factors crucial for aging and longevity. For example, the analysis of the SOD2 gene helps determine antioxidant capacity.
4. Dietary Preferences and Sensitivities
This component explores genetic predispositions to specific tastes and sensitivities, enabling the creation of diets tailored to individuals.
By addressing these parameters, MAGISNAT supports scientifically precise nutritional supplementation, fostering balance and preventing deficiencies.
Managing Inflammation and Oxidative Stress: A Comprehensive Approach
MAGISNAT's application of omics sciences emphasizes the management of inflammation and oxidative stress—key factors in maintaining health and supporting individuals facing chronic diseases. Detailed marker analysis allows for personalized recommendations to optimize antioxidant use and balance inflammatory responses, enhancing immunity and minimizing chronic inflammation.
A cornerstone of MAGISNAT's approach is the customization of macronutrient metabolism. Understanding how the body metabolizes carbohydrates, lipids, and proteins enables the creation of scientifically personalized dietary plans. For instance, genetic variants in PPARG and APOA5 genes influence lipid metabolism and triglyceride levels. Such insights guide tailored recommendations to support cardiovascular health and weight management.
General Wellness Tests: Personalized Solutions for Complex Conditions
MAGISNAT is introducing a dedicated category of General Wellness Tests, DNA Lifestyle Optimizer Test to support individuals managing complex conditions such as obesity, lipedema, and lymphedema. These tests provide valuable genetic insights to guide personalized nutritional and lifestyle strategies, empowering patients to take proactive steps toward improving their overall wellness.
Genetic Testing CAP/CLIA LTDs: Launching a New Era of DNA Tests
In addition to wellness-focused solutions, MAGISNAT will release a comprehensive suite of genetic tests (CAP/CLIA LTDs) by 2025, targeting Mendelian disorders and genetically influenced conditions. These include obesity, lipedema, lymphedema, vascular malformations, cardiac genetic diseases, hypercholesterolemia, hypertriglyceridemia, diabetes, hypothyroidism, hyperthyroidism, and inflammatory bowel diseases. These genetic LTDs aim to bridge the gap between advanced diagnostics and practical health interventions, delivering precise and actionable solutions for patients and healthcare providers alike.
Genetic Testing and Wellness Solutions for Athletes
For athletes, MAGISNAT will offer both Genetic Testing LTDs and General Wellness Tests tailored to optimize performance and address hereditary risks. The Genetic Testing LTDs provide comprehensive screening for genes associated with conditions that may impact athletic performance or overall health. Meanwhile, the General Wellness Tests focus on enhancing fitness, recovery, and endurance through personalized insights into nutrition, metabolism, and muscle function. Together, these tools empower athletes to achieve peak performance while proactively managing their genetic predispositions.
Health and Microbiome Monitoring
Health is central to overall wellness, impacting immunity and nutrient absorption. MAGISNAT integrates oral, gut, skin, microbiome analysis into its approach to personalize dietary supplementation, enhancing body microflora and addressing nutritional imbalances.
Continuous Support through App-Based Monitoring
Looking to the future, MAGISNAT is developing dedicated apps for continuous wellness monitoring. These tools will provide real-time advice on diet, exercise, and weight management. By offering personalized guidance for conditions like lipedema and lymphedema, or athlets these apps empower users to take proactive control of their well-being. While not a substitute for medical diagnosis, they represent a valuable resource for self-care management.
Nutraceutical Supplements: Seven Lines for Diverse Needs
MAGISNAT pairs its omics testing with a range of scientifically formulated, certified supplements tailored to the specific needs identified by genetic and molecular tests. These supplements are organized into seven lines:
1. Green Line: Immune system support with antioxidant-rich ingredients.
2. Orange Line: Solutions for targeted conditions, including obesity, lymphedema, and lipedema.
3. Yellow Line: Longevity and oxidative stress defense to counter premature aging.
4. Blue Line: Enhanced physical performance through energy-boosting nutrients.
6. Red Line: Solutions for nutritional deficiencies and increased demands.
7. Light Blue Line: Microbiome regulators and improve digestion and intestinal health.
The "OMICS Machine": Mapping Molecular Health
The OMICS Machine is the pinnacle of MAGISNAT’s scientific methodology. This system integrates data from omics testing to map key molecular pathways. By pinpointing vulnerabilities and suggesting ideal interventions, the OMICS Machine ensures precise rebalancing of molecular mechanisms. Users can track progress and adapt their supplementation plans, making wellness a dynamic and interactive process.
Commitment to Quality and Transparency
MAGISNAT upholds the highest standards of quality and safety. All supplements are manufactured in compliance with GMP standards and tested for heavy metals, pesticides, and allergens. Certificates of analysis for each batch are published on the company’s website.
MAGISNAT’s Mission: Accessible Personalized Wellness for All
Founded by Dr. Matteo Bertelli, a molecular geneticist, MAGISNAT draws inspiration from the pioneering work of Achille Bertelli, who began exploring the potential of natural molecules for prevention in 1879 in San Francisco (USA). Today, MAGISNAT continues this legacy, applying cutting-edge omics science to meet individual health needs. Through its integrated approach, MAGISNAT delivers scientifically supported solutions for those seeking proactive, personalized wellness.
A Year of Achievements and a Vision for the Future
In its first year, MAGISNAT has proven that scientifically personalized wellness is an attainable reality, transforming prevention into a daily routine. With a vision of expanding this approach, MAGISNAT aims to make wellness science accessible to everyone, fostering a global community that embraces the power of personalized prevention.
Article Disclaimer: These statements have not been evaluated by the Food and Drug Administration. It is important to note that this article does not intend to provide medical advice, and the purpose of the summary of scientific bibliography is cultural insight. The article does not suggest that omic tests have any therapeutic, diagnostic, or preventive properties for any disease or condition. It is not intended as advice to use omics tests in any modality or for any purpose. Only a physician and/or nutritionist can provide advice in the areas of nutrition, prevention, and health.
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